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Disability News Last Updated: May 5th, 2009 - 13:34:00


Disability News - Suicide
By Trish Blair
May 4, 2009, 13:32

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DISABILITY NEWS

May 4, 2009

A SERIOUS TOPIC

Suicide is a something that affects almost everyone at some point in their lives. Whether it be a friend, relative or friend of a friend, it is likely that we all know someone who has committed suicide. The psychological underpinnings of what causes one to commit suicide are constantly being examined. A recent article at CNN.com provided some information regarding genetic implications of suicide.

By Elizabeth Landau
(CNN) -- The poet Sylvia Plath, who made a name for herself through prose and poetry that conveyed a sense of depression and suicidal tendencies, famously died by asphyxiating herself in an oven in 1963.
The recent reported suicide of her son, marine biologist Nicholas Hughes, brings to light a known psychiatric phenomenon: the heredity of suicidal behavior.
A first-degree relative -- a parent, sibling or child -- of a person who has committed suicide is four to six times more likely to attempt or complete a suicide, said Dr. David Brent, psychiatrist at the University of Pittsburgh Medical Center. Studies on twins have shown that suicidal behavior is between 30 and 50 percent due to heritable factors, he said. Suicide victims' biological relatives who were adopted away also show an increased risk of suicide, he said.
The rate of suicide in America is 10.9 suicide deaths per 100,000 people, according to the latest information from the National Institute of Mental Health. That means, although the likelihood of suicidal behavior increases in families, a completed suicide is still a rare event, Brent said.
"Genetics is not destiny," he said. "The odds are still very much against you having this happening to another relative."
Family history of suicide and family history of mental disorder are two risk factors that the National Institute of Mental Health lists. More than 90 percent of people who die by suicide have depression or another mental disorder, or a substance abuse disorder in combination with another mental problem, according to the National Institute of Mental Health.
Research shows that depression runs in families. A new study in the Proceedings of the National Academy of Sciences shows biological markers for the inherited condition. The researchers found, in a sample of 131 people, that the biological offspring of depressed people had structural differences in their brain. Some of these people had been followed for more than 25 years.
People at high risk of developing depression had a 28 percent thinning of the right cortex, the brain's outermost surface, the study found. Those with an extra thinning abnormality in the left cortex were most likely to develop depression or anxiety.

The new study may point toward more individualized medicine -- one day people may be screened for these brain abnormalities that indicate high depression risk, and receive treatment based on that, he said.
Researchers believe the cortical thinning causes depression by interfering with the processing of emotional stimuli, he said. A person with these brain abnormalities may benefit from therapy targeted at responding to social stimuli more appropriately, he said.
With both depression and suicide, research suggests that causal factors are a combination of genetics and environment, Peterson said.
The best way to prevent suicide is to treat the underlying psychiatric disorder, Brent said.
Besides Hughes and Plath, famous examples of two or more close relatives committing suicide include Ernest Hemingway's family -- Hemingway's father, brother, sister and granddaughter, in addition to the famous novelist himself, killed themselves.
The poet John Berryman jumped off a Minneapolis bridge in 1972; his father had committed suicide when the poet was a child. More recently, the playwright Spalding Gray apparently killed himself in 2004; his mother had taken her own life many years earlier.
Do relatives of people who killed themselves imitate suicide? This is possible, but hard to prove or disprove, Brent said. In fact, there is more evidence of copycat suicides among people who did not know the victim well, but merely learned about him or her through the news...

Comments? Trish-blair@redwoods.edu

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(Robert Frost)

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